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1.
perplexed exclamation denoting confusion or suprise in reaction to another party's previous statement or action.
teacher: This paper should be 42 pages long.

student: jigga-WHAT?!
av pylocatabasis 6 januari 2004
 
2.
A reaction of disbelief when somebody says something absurd or outrageous.
"His girlfriend was caught cheating on him."

"Jiggawhat!?!?!"
av Lovbugg 23 maj 2009
 
3.
A declaration of surprise or inquiry used when addressing an African-American Jew, AKA a "Jigga".
Someone's stolen your menorah? Jigga what?
av Angus98 5 april 2004