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1.
A blanket term for higher quality marijuana.
Synonym: dank
Stoner A: Hey man, you got any drough?
Cannabis Provider: Yessir, straight drough, no seeds no stems.
Stoner A: Far out dude, I'm really getting sick of sorting through seeds.

Example 2. "Blow that drough!"
av BLOWDATDROUGH 3 december 2009
 
2.
pronounced like "drew" means anything that rhymes with you.
what are drough droughing? (what are you doing?)
av Drough 24 september 2005
 
3.
Drugs of some type, I think.
Yo, check out this drough I gots. It's the shiznit.
av Christopher B 21 juli 2006