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1.
1.) Figurative: A metaphorical phrase for that which affects a person directly, or is of personal concern to him or her.

2.) Literal: Within close proximity to a person's home or dwelling.
Drunk Driving is a subject that hits close to home with members of MADD.

The bombs hit close to home last night; they were only a few miles away.
av Dispatch Kick Ass 16 juli 2004
 
2.
'Close to Home' simply means the act of committing something less than savoury with your girls best friend.
Dumbass A; Dude i just totally boned Finola's best friend!

Dumbass B; Man! That was a bit close to home wasn't it?

Dumbass A; Yea, but as long as i be hitting that sweet ass - it's all gravy.
av Jingles 23 juli 2004
 
3.
Slang used to describe the act of cunnilingus, referencing that all human's original "home" was the womb.
After a few minutes of making out, it was time to get close to home.
av Media Assassin 22 juli 2004
 
4.
To cornhole. See Cornholing
Hey lets go close to home
av Baier 19 juli 2004